Post MI Myocardial Infarction

Myocardial infarction (also known as heart attack) is responsible for significant cardiac destruction due to ischemia (lack of blood flow). This can lead to further or recurrent infarct, chronic angina and heart failure. With injury or destruction to heart cells, white blood cells may descend upon the injury, recruit fibroblasts and ultimately leave scar tissue in place of once healthy and functional muscle tissue.  This problem is caused most commonly by coronary vessel disease which is very common in the United States and associated with significant morbidity and mortality.    Cell therapy potentially offers an important solution for Post MI Myocardial Infarction.  During cardiac ischemia, millions of myocytes are lost resulting in loss of contractile function. One of the great goals of regenerative medicine is to engineer methods of replacing these cells.  Recently adipose-derived mesenchymal stem cells appear to be playing an important role in this regeneration. There is also a growing body of data supporting the use of engineered biologics such as selected cell populations, organic scaffolds, and modified (differentiated or de-differentiated) stem cells to regenerate damaged myocardium. It is unknown whether the cost of engineered biologics over harvested stem cells is justified until long-term studies are available. The results of clinical trials of the use of adult mesenchymal stem cells to treat cardiac disease have demonstrated safety and most have shown positive clinical results. Mesenchymal stem cells have been deployed intravenously, injected the myocardium, and placed in the coronary arteries and it is still unclear if one delivery method is clearly superior to another. It is also unclear which source of mesenchymal cells is optimal for cardiac regeneration but adipose-derived cells appear to be highly effective in this area.  There is reason to believe, that just as concussion has been shown to be most effectively treated within the first 24hrs., it’s likely the same applies to the heart.  Once vascular patency is re-established, then it likely would be most optimal to provide personal cell therapy as soon as possible to repair or start replacing injured or dead myocardiocytes.

Why Personal Cell Therapy With Adipose-Derived Stem Cells?

Personal cell therapy with adipose-derived stem cells represents an ideal way of repairing injuries and medical conditions.  Our bodies are made of cells and every injury or medical condition represents some kind of cell damage.  If we can repair or replace our injured or ailing cells with functional cells, then we can restore normal function and/or reduce pain and dysfunction that results.  

Stem cells are uniquely capable of repairing or replacing damaged cells but their ability to do that really depends on two things – a) the state of the condition or injury and b) the presence of adequate numbers and functioning stem cells.  Since we can generally obtain a very high number of functioning cells from your own adipose tissue and even grow your own cells in a laboratory environment, we should be able to provide adequate numbers of cells.  The state of your injury is something that can’t always know – sometimes we can imply that your injury will be responsive to cell therapy based upon how it responded to other therapies (e.g. steroids), but without visualizing or having pathology samples we must infer or simply treat the condition to ascertain its ability to respond.  We know from a variety of studies that the sooner you treat a problem, the easier it is to predict a satisfactory result.  Also, some conditions require drug or surgical intervention to optimize their ability to be repaired.  If there is an infection, it needs to be treated before you can repair the damage.  If there’s a fracture it needs to be stabilized before you can help it repair.  If there’s scar tissue, then it may need to be removed before you can restore normal tissue function.  

Since beginning investigative treatments in 2010 we have acquired extensive clinical data and seen our treatment results recapitulated by hundreds of other physicians.  As such, we do not consider these interventions “experimental” but rather “investigative” as we accumulate more data to help us advance personal cell therapy as an important, if not essential arm of medical and surgical procedures.  It is important to understand that these are your own cells, and not subject to FDA oversight,  as they are isolated for your own personal use during the same-day surgical procedure.  We can do double-blind studies but our current data speaks for itself.   Tens of thousands of patients have tried numerous interventions prior to stem cell therapy –  without improvement,  so when they improve following delivery of their own SVF cells, it’s highly unlikely that this is a placebo effect. 

Schedule your FREE Consultation

Do you have additional questions on how stem cells work and how they relate to your condition?  Contact us today to schedule your no-obligation consultation today. To get the process started, simply fill out our short stem cell candidate form. Once we receive the application, a stem cell coordinator will call you to schedule your complimentary consultation. We look forward to educating you on the latest research for stem cell therapy.